Description
According to studies, the PTEN gene, which corresponds to chromosome 10q23, is a tumour suppressor gene. PTEN is a new tumour suppressor that controls apoptosis and the course of the cell cycle. 15–16 The PTEN gene may be mutated or deleted, which could lead to a novel signal transduction pathway associated with malignant tumours in humans. Research has shown that advanced breast tumours exhibit decreased PTEN expression. 15.
Specifications
| Intended Use | IVD |
|---|---|
| Format | Concentrate, ONCORE Pro, Predilute, Q Series, UltraLine |
| Source | Mouse Monoclonal |
| Clone | 6H2.1 |
| Isotype | IgG |
| Antigen | PTEN |
| Localization | Cytoplasmic |
| Positive Control | Some breast, renal cell and prostate carcinomas |
| Species Reactivity | Human, Mouse |
